This study was designed to investigate physiological and psychological char
acteristics of subjects with high-frequency emergency room (ER) visits. Ast
hma status, psychological functioning and predispositions, psychosocial ada
ptation to asthma, and health behaviors were measured for 30 patients who h
ad two or more ER visits during the last 2 years. These subjects were match
ed for age, sex, and corticosteroid use with 30 subjects who had no unsched
uled ER visits for the same period. No significant differences were found f
or measures of asthma status. Among the asthma-specific variables, the numb
er of hyperventilation-bronchoconstriction symptoms did not distinguish bet
ween the groups. High attenders reported more panic-fear symptoms, lower se
lf-efficacy, and more perceived interference. There were no differences for
measures of anxiety/depression, self-focused attention, or health locus of
control. However, these variables were found to be significant predictors
of panic-fear symptoms, lower self-efficacy, and more perceived interferenc
e.