New bitter diterpenes, rabdosianone I and II, isolated from Isodon japonicus Hara

Authors
Yamada, Y Sako, N Ando, E Yamada, M Kikuzaki, H Yamamoto, T
Citation
Y. Yamada et al., New bitter diterpenes, rabdosianone I and II, isolated from Isodon japonicus Hara, BIOS BIOT B, 63(3), 1999, pp. 524-529
Citations number
15
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
63
Issue
3
Year of publication
1999
Pages
524 - 529
Database
ISI
SICI code
0916-8451(199903)63:3<524:NBDRIA>2.0.ZU;2-Z
Abstract
The new bitter diterpenes, rabdosianone I(C20H24O5) and II (C22H28O6), were isolated from Isodon japonicus (Japanese name, enmeiso), and their structu res were elucidated by spectroscopic methods, Electrophysiological experime nts were performed to compare rabdosianone I with quinine. The taste respon ses of chorda tympani nerves to rabdosianone I were smaller than those to q uinine in Wistar rats.