An uncommon case of late thrombotic thrombocytopenic purpura (42 months) after autologous peripheral blood stem cell (PBSC) transplantation in a child

Thrombotic thrombocytopenic purpura (TTP) is a serious complication followi ng bone marrow transplantation (BMT). Therapeutic plasma exchange does not appear to be effective in its management in contrast to classical TTP. We r eport the case of a child with TTP 3 years after autologous PBSC transplant ation, in whom remission was achieved by administration of cyclosporin A, a fter failure of plasmapheresis as primary treatment.