Improvement of the enantioselectivity in the enantioselective hydrogenation of ethyl pyruvate by addition of achiral tertiary amines

Authors
Margitfalvi, JL Talas, E Hegedus, M
Citation
Jl. Margitfalvi et al., Improvement of the enantioselectivity in the enantioselective hydrogenation of ethyl pyruvate by addition of achiral tertiary amines, CHEM COMMUN, (7), 1999, pp. 645-646
Citations number
13
Categorie Soggetti
Chemistry
Journal title
CHEMICAL COMMUNICATIONS
ISSN journal
13597345 → ACNP
Issue
7
Year of publication
1999
Pages
645 - 646
Database
ISI
SICI code
1359-7345(19990407):7<645:IOTEIT>2.0.ZU;2-X
Abstract
In the asymmetric hydrogenation of ethyl pyruvate over the catalyst system cinchonidine-Pt/Al2O3 the enantioselectivity was significantly improved by addition of different achiral tertiary amines to the reaction mixture, howe ver the effect appeared to be strongly solvent and concentration dependent.