We present a knowledge-based approach to segmentation and analysis of the l
ung boundaries in chest X-rays. Image edges are matched to an anatomical mo
del of the lung boundary using parametric features. A modular system archit
ecture was developed which incorporates the model, image processing routine
s, an inference engine and a blackboard. Edges associated with the lung bou
ndary are automatically identified and abnormal features are reported. In p
reliminary testing on 14 images for a set of 18 detectable abnormalities, t
he system showed a sensitivity of 88% and a specificity of 95% when compare
d with assessment by an experienced radiologist. (C) 1999 Elsevier Science
Ltd. All rights reserved.