DNA structure and transcription

Authors
Dai, X Rothman-Denes, LB
Citation
X. Dai et Lb. Rothman-denes, DNA structure and transcription, CURR OPIN M, 2(2), 1999, pp. 126-130
Citations number
50
Categorie Soggetti
Biotecnology & Applied Microbiology",Microbiology
Journal title
CURRENT OPINION IN MICROBIOLOGY
ISSN journal
13695274 → ACNP
Volume
2
Issue
2
Year of publication
1999
Pages
126 - 130
Database
ISI
SICI code
1369-5274(199904)2:2<126:DSAT>2.0.ZU;2-0
Abstract
Regulation of transcription occurs through complex interactions of RNA poly merase and accessory proteins with specific DNA sequences and with each oth er. The DNA template topology influences the interaction of RNA polymerase with the promoter and its response to repressors, activators and the intrac ellular milieu through the formation of altered DNA structures or of nucleo protein complexes. Recent developments on the role of DNA structures in tra nscription regulation are discussed.