Al. Kellermann et al., PREDICTING THE OUTCOME OF UNSUCCESSFUL PREHOSPITAL ADVANCED CARDIAC LIFE-SUPPORT, JAMA, the journal of the American Medical Association, 270(12), 1993, pp. 1433-1436
Objective.-To determine if failure to achieve return of spontaneous ci
rculation following prehospital advanced cardiac life support (ACLS) w
arrants termination of efforts at the scene. Design.-Retrospective cas
e series. Setting.-Memphis, Tenn, a city of 610337 people that is serv
ed by a fire department-based emergency medical service system. All ci
ty ambulances provide ACLS. Patients.-Adult victims of out-of-hospital
cardiac arrest due to heart disease. Intervention.-All patients recei
ved prehospital ACLS according to the 1986 American Heart Association
guidelines. Following prehospital ACLS, all patients were transported
to the nearest hospital emergency department whether or not a pulse wa
s restored in the field. Main Outcome Measures.-Survival to hospital a
dmission, survival to hospital discharge, and neurological status at d
ischarge. Results.-Over the 39-month study interval, the Memphis Fire
Department treated 1068 victims of out-of-hospital cardiac arrest. Thr
ee hundred ten of these (29%) had return of spontaneous circulation pr
ior to transport for some period. The remaining 758 patients (71%) nev
er regained a pulse and were transported with ongoing cardiopulmonary
resuscitation. Patients who had return of spontaneous circulation prio
r to transport were more likely to be admitted (69% vs 7.0%) and far m
ore likely to be discharged alive (26.5% vs 0.4%) than patients who fa
iled to respond to prehospital ACLS. Three patients who survived to ho
spital discharge despite failure to achieve return of spontaneous circ
ulation prior to emergency medical service transport sustained their c
ardiac arrest after paramedic arrival. All three were discharged with
moderate to severe cerebral disability. Conclusion.-Rapid transport of
adults who fail to respond to an adequate trial of prehospital ACLS d
oes not result in meaningful rates of survival. In such cases, on-line
emergency medical service physicians should authorize paramedics to c
ease efforts in the field.