Amelioration of acromegaly after pituitary infarction due to gastrointestinal hemorrhage from gastric ulcer

We report a rare case of acromegaly in which pituitary infarction possibly developed in a GH-producing pituitary adenoma following gastrointestinal bl eeding from peptic ulcer. In this case, pituitary infarction resulted in sp ontaneous remission of acromegaly associated with diabetes mellitus. In add ition, detailed histological investigation revealed that clinically silent pituitary apoplexy was mainly an acute ischemic event which occurred recent ly in a GH-producing adenoma. This event led to massive coagulation necrosi s of the tumor and endocrinological improvement.