Resolution of disseminated molluscum contagiosum with Highly Active Anti-Retroviral Therapy (HAART) in patients with AIDS

Molluscum contagiosum (MC), a cutaneous infection caused by a DNA virus bel onging to the poxvirus group, affects about 5-10% of patients with HIV dise ase, often showing extensive, severe lesions, unresponsive to therapy [1]. During the follow-up of three patients with AIDS for MC recalcitrant to the rapy, we noted their cutaneous lesions cleared 5-6 months after they had be gun Highly Active Anti Retroviral Therapy (HAART). This therapy includes an HIV protease inhibitor (indinavir) and two reverse transcriptase inhibitor s [2, 3].