A prospective study was carried out to determine the accuracy of spiral CT
angiography (CTA) in the detection of renal artery stenosis (RAS). Eighty-t
wo patients with arterial hypertension underwent CTA and digital subtractio
n angiography (DSA) to exclude RAS. For CTA a contrast medium bolus of 100-
150 ml (flow rate 3 ml/s) was injected. A 24 or 40 s CTA was started at the
origin of the superior mesenteric artery after a delay time determined by
test bolus injection (collimation = 2 mm, - pitch = 1/1.5). For stenosis de
tection transverse images supported by maximum intensity projections (MIP)
or multiplanar reconstruction projections were used. Of 197 renal arteries
examined (including 33 accessory arteries), 34 RAS were visualized using DS
A. With CTA, one hemodynamic RAS was missed and one additional hemodynamic
RAS was found. Sensitivity/specificity was calculated to be 94%/ 98%. For h
emodynamically relevant RAS (> 50%) the sensitivity/specificity was 96%/99%
. CTA additionally depicted five adrenal masses. The high accuracy rate of
RES detection thus allows the use of CTA as a screening method in patients
with arterial hypertension to exclude a renovascular cause.