Porin OmpC from Escherichia coli was reconstituted in liposomes and its gat
ing kinetics were recorded at high hydrostatic pressure, up to 90 MPa, usin
g a development of the patch clamp technique. The composition of the record
ing solution influenced the results but generally high hydrostatic pressure
favoured channel opening. (C) 1999 Federation of European Microbiological
Societies. Published by Elsevier Science B.V. All rights reserved.