B cell mucose-associated lymphoid tissue multifocal lymphoma and cytomegalovirus gastritis associated with CD4+T lymphocytopenia without HIV infection.

We report the case of a 63 year-old female who presented with a seven-year history of epigastric pain and a sudden overall deterioration. Gastroscopy demonstrated inflammatory aspect and ulceration in the antrum and fundus. H istology showed a lymphocytic infiltrate consistent with low grade mucosa-a ssociated lymphoid tissue lymphoma and cytomegalovirus gastritis. There was no evidence of Helicobacter pylori infection. Other investigations demonst rated two pulmonary foci consistent with lymphomatous infiltration and a re duced CD4 + T-lymphocyte count (85/mm(3)). Other screening tests including HIV serology were negative. This case of idiopathic CD4 lymphopenia, in con junction with the other rare cases in the literature, allows us to reevalua te this condition and its unusual clinical presentation with two opportunis tic pathologies.