Reports in the literature of an increasing incidence of endometriosis in in
dustrialized countries and increasing problems with pollution in these coun
tries leads to speculation about a possible link between one of the most ha
rmful components of pollution, dioxin, and endometriosis. To establish this
link, we need to examine three issues more closely: What are the effects o
f dioxin, what is the true incidence of endometriosis, and what is the natu
re of the association between endometriosis and dioxin. This report reviews
current thinking on these issues.