We studied the histories of eight patients who lacked clear evidence of car
diac abnormalities other than marked bilateral atrial dilatation and atrial
fibrillation, which have rarely been discussed in the literature, From the
time of their first visit to our hospital, the patients' chest radiographs
and electrocardiograms showed markedly enlarged cardiac silhouettes and at
rial fibrillation, respectively, Each patient's echocardiogram showed a mar
ked bilateral atrial dilatation with almost normal wall motion of both vent
ricles, In one patient, inflammatory change was demonstrated by cardiac cat
heterization and endomyocardial biopsy from the right ventricle, Seven of o
ur eight cases were elderly women, Over a long period after the diagnosis o
f cardiomegaly or arrhythmia, diuretics or digitalis offered good results i
n the treatment of edema and congestion in these patients. In view of the c
linical courses included in the present study, we conclude that this disord
er has a good prognosis.