Electrokinetic injection in capillary electrophoresis and its application to the analysis of inorganic compounds

In capillary electrophoresis, electrokinetic injection is a highly controve rsial sampling technique. It is a simple mode of sample introduction which is suitable for on-line preconcentration of the analytes, but its precision and accuracy are more strongly affected by experimental conditions compare d to hydrodynamic injection. In the first part of this paper the features o f electrokinetic and hydrodynamic injections are compared, followed by a de tailed discussion on the different biases of electrokinetic injection and o n how to reduce them. Finally, applications of the electrokinetic injection are reviewed with special emphasis on the analysis of inorganic compounds. (C) 1999 Elsevier Science B.V. All rights reserved.