A retrospective survey of 262 carotid endarterectomies performed in the Neu
rosurgical Unit at Royal Prince Alfred Hospital over a 15 year period was c
onducted. A total of 141 patients were operated on for transient ischaemic
attacks referable to stenosis of the ipsilateral internal carotid artery. E
ighty-eight percent of patients had angiographic evidence of greater than 8
0% stenosis of the affected internal carotid artery. A postoperative new pe
rmanent neurological deficit of 1.9% and death rate of 0.6% was achieved. N
o deaths and two postoperative strokes were recorded after 1987. These resu
lts are comparable with published series. The use of barbiturate therapy wi
th electroencephalography changes on cross clamping of the internal carotid
artery is described.