We report a case of thyrotoxicosis associated with chorea and detectable an
ti-phospholipid antibodies in which a structural abnormality could not be d
etected on routine imaging but cerebral perfusion single photon emission co
mputed tomography scans suggested a reversible alteration of basal ganglia
perfusion. The pathophysiological mechanisms of phospholipid antibody causi
ng chorea in thyrotoxicosis are discussed. Journal or Clinical Neuroscience
(1999) 5(2), 168-171 (C) 1999 Harcourt Brace & Co. Ltd.