P. Schmidely et al., Influence of feed intake and source of dietary carbohydrate on the metabolic response to propionate and glucose challenges in lactating goats, J DAIRY SCI, 82(4), 1999, pp. 738-746
The influence of type of nutrients in the diet (rapidly degraded starch plu
s rapidly degraded N or highly digestible fiber plus slowly degraded N) and
amount of feed offered (2.40 +/- 0.10 or 2.00 +/- 0.10 kg of dry matter/d)
on plasma constituents after a glucose tolerance test or a propionate chal
lenge test were studied using 12 multiparous dairy goats. Type of diet and
interaction between type of diet and amount of feed offered had no effect o
n the concentrations of any plasma metabolite measured during propionate ch
allenge. During propionate challenge, goats fed at the high dry matter inta
ke (DMI) had a higher clearance of propionate and glucose and a higher rati
o of plasma insulin to glucose. During glucose challenges, goats fed diets
that were rich in highly digestible fiber tended to have lower peak concent
rations of glucose, and goats fed at the high DMI had a higher clearance of
glucose. The plasma insulin response to the glucose test was not altered b
y treatment. The ratio of plasma insulin to glucose was numerically, althou
gh nonsignificantly, higher for goats fed at the high rate of DMI. Most of
the differences concerning glucose metabolism, insulin response, and tissue
responsiveness to insulin appeared to be primarily due to the amount of fe
ed offered and not to the type of diets fed to dairy goats in midlactation.