ASYMMETRIC OXIDATION OF SULFIDES BY CYCLOHEXANONE MONOOXYGENASE

Authors
SECUNDO F CARREA G DALLAVALLE S FRANZOSI G
Citation
F. Secundo et al., ASYMMETRIC OXIDATION OF SULFIDES BY CYCLOHEXANONE MONOOXYGENASE, Tetrahedron : asymmetry, 4(9), 1993, pp. 1981-1982
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
4
Issue
9
Year of publication
1993
Pages
1981 - 1982
Database
ISI
SICI code
0957-4166(1993)4:9<1981:AOOSBC>2.0.ZU;2-J
Abstract
Cyclohexanone monooxygenase catalyzes the asymmetric oxidazion of nume rous alkyl aryl sulfides with the alkyl chain functionalyzed with Cl, CN, vinyl or hydroxy groups. Sulfoxides with enantiomeric excesses up to 99% were obtained. The structure of the sulfide markedly influenced enzyme enantioselectivity.