Endocytosis of dextran and silan-coated magnetite nanoparticles and the effect of intracellular hyperthermia on human mammary carcinoma cells in vitro

Authors
Jordan, A Scholz, R Wust, P Schirra, H Schiestel, T Schmidt, H Felix, R
Citation
A. Jordan et al., Endocytosis of dextran and silan-coated magnetite nanoparticles and the effect of intracellular hyperthermia on human mammary carcinoma cells in vitro, J MAGN MAGN, 194(1-3), 1999, pp. 185-196
Citations number
17
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science
Journal title
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
ISSN journal
03048853 → ACNP
Volume
194
Issue
1-3
Year of publication
1999
Pages
185 - 196
Database
ISI
SICI code
0304-8853(199904)194:1-3<185:EODASM>2.0.ZU;2-9
Abstract
To obtain more evidence for intracellular magnetic fluid hyperthermia (MFH) , endocytosis and hyperthermia efficacy of silan and dextran magnetite was investigated. Differential endocytosis was observed in dependence of nanopa rticle and cell type. Clonogenic survival was 3-fold lower after MFH versus waterbath hyperthermia. The selective "remote inactivation" of cancer cell s by an AC magnetic held has been demonstrated in vitro. (C) 1999 Elsevier Science B.V. All rights reserved.