Lymphatic mapping and sentinel node location with magnetite nanoparticles

Authors
Jung, CW Rogers, JM Groman, EV
Citation
Cw. Jung et al., Lymphatic mapping and sentinel node location with magnetite nanoparticles, J MAGN MAGN, 194(1-3), 1999, pp. 210-216
Citations number
24
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science
Journal title
JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS
ISSN journal
03048853 → ACNP
Volume
194
Issue
1-3
Year of publication
1999
Pages
210 - 216
Database
ISI
SICI code
0304-8853(199904)194:1-3<210:LMASNL>2.0.ZU;2-R
Abstract
Subcutaneously administered magnetite nanoparticles were used to locate sen tinel lymph nodes in normal rats. Nanoparticles sequestered in brachial and axillary lymph nodes produced magnetic susceptibility artifacts in gradien t recall echo magnetic resonance images. The artifact sizes enabled the det ermination of nanoparticle nodal uptake rates and lymphatic drainage patter ns. These studies were confirmed by use of Fe-59 labeled magnetite nanopart icles. (C) 1999 Elsevier Science B.V. All rights reserved.