OBJECTIVES: To examine the presence or absence of dementia, and the prevale
nce rates for different dementias, in patients with and without adult onset
diabetes (AODM).
DESIGN: Chart survey.
SETTlNG: A public long-term care facility in Rochester, New York, chosen to
provide an enriched sample with respect to the diseases and demographic va
riables of interest.
PARTICIPANTS: All long-term care residents in the facility aged 50 years or
older (n = 476), mean age 74.8 years. Thirty-six (7.6%) had probable Alzhe
imer's disease (AD), 49 (10.3%) had possible AD, 38 (8.0%) had clinically d
iagnosed vascular dementia, 84 (17.6%) had unspecified dementias, and 269 (
56.5%) were not demented.
MEASUREMENTS: Demographic data, dementia and diabetes determined on the bas
is of extraction of chart data, and hypertension, myocardial infarction, co
ngestive heart failure, and hypercholesterolemia determined on the basis of
chart diagnoses.
RESULTS: There were 99 residents with AODM in the sample, a prevalence rate
of about 21%. The rates of both dementia and AODM were as expected for thi
s age group and setting. Patients with probable or possible AD had the lowe
st rates of AODM (0 and 6.1%, respectively), and patients with vascular dem
entia had the highest rates of AODM (47.4%). Age, sex, and race influenced
both the risk of having a dementia and the type of dementia. When these var
iables were adjusted for in multiple logistic regression, however, AODM rem
ained a robust predictive factor because of its significant negative associ
ation with AD. Patients with unspecified dementias and no dementia showed r
ates of AODM (about 20%) that were roughly comparable and intermediate betw
een vascular dementia and AD.
CONCLUSIONS: In our study, AD diagnosed clinically and AODM did not co-occu
r, whereas AODM was associated with vascular dementia diagnosed clinically.
Conversely, in non-Alzheimer, nonvascular dementias diagnosed clinically,
the rates of AODM were equivalent to those in nondemented patients. These f
indings are in agreement with some, but not all, previous studies.