Neuroinvasion by human herpesvirus type 7 in a case of exanthem subitum with severe neurologic manifestations

Authors
van den Berg, JSP van Zeijl, JH Rotteveel, JJ Melchers, WJG Gabreels, FJM Galama, JMD
Citation
Jsp. Van Den Berg et al., Neuroinvasion by human herpesvirus type 7 in a case of exanthem subitum with severe neurologic manifestations, NEUROLOGY, 52(5), 1999, pp. 1077-1079
Citations number
10
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
52
Issue
5
Year of publication
1999
Pages
1077 - 1079
Database
ISI
SICI code
0028-3878(19990323)52:5<1077:NBHHT7>2.0.ZU;2-X
Abstract
A 19-month-old girl presented with severe neurologic symptoms associated wi th exanthem subitum. Human herpesvirus type 7 (HHV-7) DNA was detected in t he CSF and serum, and supported by serologic studies. The patient was diagn osed with encephalopathy due to an acute HHV-7 infection. Neuron-specific e nolase in the CSF was strongly elevated during the acute stage of infection , suggesting that the encephalopathy was due to viral invasion of the brain .