Background-Objective: Grapheme-to-phoneme conversion (GPC) allows the pronu
nciation of nonword letter strings and of real words with which the literat
e reader has no previous experience. Although cross-modal association betwe
en visual (orthographic) and auditory (phonemic-input) representations may
contribute to GPC, many cases of-deep or phonologic alexia result from inju
ry to anterior perisylvian regions. Thus, GPC may rely upon associations be
tween orthographic and articulatory (phonemic-output) representations. Meth
od-Results-Conclusion: Detailed analysis of a patient with phonologic alexi
a suggests that defective knowledge of the position and motion of the artic
ulatory apparatus might contribute to impaired transcoding from letters to
sounds.