Clinical studies have provided convincing evidence that early nutritional s
upport benefits the metabolically stressed surgical patient, but the optima
l route of substrate delivery, enteral or parenteral, continues to be debat
ed. Optimal nutritional support following major torso trauma may best be pr
ovided via early enteral feeding. This article defines optimal nutrition fo
llowing major torso trauma based on recently reported basic and clinical in
vestigation, and describes a systematic method to deliver nutritional care
in the ICU based on ongoing investigation. Part I reviews clinical evidence
to support the conclusions that early nutrition following major torso trau
ma improves outcome, that the enteral route is preferred over the parentera
l route, and that immune-enhancing enteral formulas should be used in selec
ted patients. Part II describes an objective expert-evidence-consensus deri
ved protocol strategy, including patient and formula selection, bedside sur
gical procedures, and nutrition management, in a multidisciplinary ICU envi
ronment. The specific mechanisms by which early enteral feeding benefits me
tabolically stressed trauma patients are not known, but it appears that the
beneficial effects of traditional nutritional support can be amplified usi
ng specific nutrients that provide immune-enhancing effects. Additional inv
estigation is needed and may provide insight to the role of the gastrointes
tinal tract in critical illness.