Priapism and increased intracranial pressure are both rare, but recognized,
manifestations of leukemia. However, they have never been reported in the
same patient. We report a 15-year-old male with acute lymphoblastic leukemi
a who presented with hyperleukocytosis, priapism, and increased intracrania
l pressure, Central nervous system leukostasis and cerebral edema may have
been detected earlier, had his history of priapism been known. Management o
f hyperleukocytosis complicated by priapism and increased intracranial pres
sure is discussed.