Elucidation of the genome organization of tobacco mosaic virus

Authors
Zaitlin, M
Citation
M. Zaitlin, Elucidation of the genome organization of tobacco mosaic virus, PHI T ROY B, 354(1383), 1999, pp. 587-591
Citations number
39
Categorie Soggetti
Multidisciplinary,"Experimental Biology
Journal title
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES
ISSN journal
09628436 → ACNP
Volume
354
Issue
1383
Year of publication
1999
Pages
587 - 591
Database
ISI
SICI code
0962-8436(19990329)354:1383<587:EOTGOO>2.0.ZU;2-6
Abstract
Proteins unique to tobacco mosaic virus (TMV)-infected plants were detected in the 1970s by electrophoretic analyses of extracts of virus-infected tis sues, comparing their proteins to those generated in extracts of uninfected tissues. The genome organization of TMV was deduced principally from studi es involving in vitro translation of proteins from the genomic and subgenom ic messenger RNAs. The ultimate analysis of the TMV genome came in 1982 whe n P. Goelet and colleagues sequenced the. entire genome. Studies leading to the elucidation of the TMV genome organization are described below.