Acetaminophen hepatotoxicity in a teenage, with excessive alcohol intake

We report a 12 years old male with a history of excessive alcohol. intake, that developed a severe liver failure after the use of acetaminophen in the rapeutic doses. He presented with encephalopathy, jaundice, fever and an up per gastrointestinal bleeding Serum aspartate aminotransferase values were 5 250 IU/L. The patient received supportive care and oral corticosteroids, remained severely compromised for 72 hours and had a good evolution thereaf ter. The association of acetaminophen use and excessive alcohol intake in a patient who developed an acute hepatic failure and the absence of serologi cal evidence of hepatitis A or B viral infection, support the diagnosis of drug induced liver failure.