SAPHO syndrome: 20-year follow-up

Considerable attention has been paid in the past 10 years to the radiologic al spectrum of disease entities belonging to the SAPHO syndrome. We report an unusual case presenting with an extra-axial (femoral) lesion, prior to d escription of this syndrome, which was radiologically and histologically mi staken for a parosteal osteosarcoma. Nineteen years later, a further lesion developed in the scapula together with the typical sternoclavicular manife stations, at which stage the correct diagnosis of SAPHO syndrome was establ ished.