Spirocycle assembly through selective tandem ring closing metathesis reactions

Authors
Bassindale, MJ Hamley, P Leitner, A Harrity, JPA
Citation
Mj. Bassindale et al., Spirocycle assembly through selective tandem ring closing metathesis reactions, TETRAHEDR L, 40(16), 1999, pp. 3247-3250
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
16
Year of publication
1999
Pages
3247 - 3250
Database
ISI
SICI code
0040-4039(19990416)40:16<3247:SATSTR>2.0.ZU;2-#
Abstract
A range of functionalised spirocyclic systems have been prepared under mild and neutral conditions by tandem selective ring closing olefin metathesis reactions. Additionally, a marked preference for 5-membered ring closure ov er 7-membered ring closure was observed which appears to be a result of a k inetically favoured cyclisation process. (C) 1999 Elsevier Science Ltd. All rights reserved.