In this paper multilayered cellular automats are formally defined as a gene
ralization of multilayered automata networks. They are hierarchically organ
ized on the basis of nested graphs, and can show different kinds of dynamic
s, which allow to use them to model, e.g., complex biological systems compr
ised of different entities organized in a hierarchical framework. Finally,
the simulation of the dynamic regulation of calcium-ion distribution in! th
e subcompartments of a living cell by means of Multilayered Cellular Automa
ta is presented, as an example that allows to show their modeling power. (C
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