Packing materials and separation efficiencies in capillary electrochromatography

Capillary electrochromatography (CEC) is a developing technique that combin es the advantages of conventional liquid chromatography (LC) with those of capillary electrophoresis. The key difference between LC and CEC is that th e latter utilizes electro-osmosis to transport the mobile phase through a c olumn, rather than hydraulic flow as in LC. As a result of the plug-like fl ow profile of electroosmosis, CEC has the potential to be more efficient th an LC. This article deals with the types of packing materials used for CEC separations and their influence on efficiency. Special attention is given t o the present status of monolithic CEC, and its future prospects. (C) 1999 Elsevier Science B.V. All rights reserved.