Ultrasonic depolymerization of the chitin-glucan complex from Aspergillus niger and antimutagenic activity of its product

Authors
Machova, E Kogan, G Chorvatovicova, D Sandula, J
Citation
E. Machova et al., Ultrasonic depolymerization of the chitin-glucan complex from Aspergillus niger and antimutagenic activity of its product, ULTRASON SO, 6(1-2), 1999, pp. 111-114
Citations number
11
Categorie Soggetti
Chemistry
Journal title
ULTRASONICS SONOCHEMISTRY
ISSN journal
13504177 → ACNP
Volume
6
Issue
1-2
Year of publication
1999
Pages
111 - 114
Database
ISI
SICI code
1350-4177(199903)6:1-2<111:UDOTCC>2.0.ZU;2-H
Abstract
Sonication was effective for the depolymerization of carboxymethylated chit in-glucan complex (CM-CG) isolated from the cell wall of Aspergillus niger. After 10 min of sonication and subsequent gel filtration, two samples (CM- CG(I) and CM-CG(II)) with significantly distinct molecular weights (660 kDa and 19 kDa, respectively) and different nitrogen contents (3.02 and 1.69%) were obtained. CM-CG(II) with lower M-w was also effective against cycloph osphamide mutagenicity by oral administration in mice. (C) 1999 Elsevier Sc ience B.V. All rights reserved.