Regeneration of abdominal wall aponeurosis: New dimension in Marlex peritoneal sandwich repair of incisional hernia

Loss of abdominal wall substance is a major cause of incisional hernia form ation. It makes repair of this iatrogenic human ailment a difficult surgica l problem. The abdominal wall substance loss has compelled the world's surg ical community dealing with this condition to substantiate the repair with extra material such as skin, fascia, wire mesh, and lately biocompatible sy nthetic mesh. Even though the synthetic mesh is compatible and well tolerat ed by body tissues, it is not without complications. Regenerative repair in the region of the abdominal wall with substance loss is probably the best repair if it can be achieved. With reasonable success in animal experiments and the positive regenerative capacity of stem cells to transform the peri toneum into an aponeurotic layer, the new technique using a Marlex peritone al sandwich for repair of large incisional hernias was attempted but was no t reported in the article published in the World Journal of Surgery in 1991 . The present study is based on experiments on seven mongrel dogs. A suitab le embryonal segment of autogenous peritoneum was excised and transfered to the rectus sheath region. The gross appearance of the grafted membrane 3 m onths after operation revealed tough, thick tissue formation. The histology confirmed the presence of collagen fiber tissue in layers similar to the a poneurosis in the grafted peritoneal membrane. The use of this regeneration in the Marlex peritoneal sandwich technique of repair of large incisional hernias and the scientific rationale of tissue regeneration by desired meta plasia is discussed.