J. Karrholm et al., FIXATION AND METAL RELEASE FROM THE TIFIT FEMORAL STEM PROSTHESIS - 5-YEAR FOLLOW-UP OF 64 CASES, Acta orthopaedica Scandinavica, 69(4), 1998, pp. 369-378
We stratified the fixation of the femoral component in 64 hips with de
generative joint disease into 3 groups, cemented (C), proximal hydroxy
apatite coating (HA) or proximal porous coating (P), All implants had
the same basic design and were made of TiAlV alloy. The migration of t
he implants was assessed by radiostereometry, After 5 years, the mean
subsidences in the cemented and porous-coated groups were 0.16 and 0.3
1 mm, whereas the HA-coated implants displayed a mean proximal migrati
on of 0.1 mm, 7 stems (2 C, 1 HA, 4 P) showed a continuous subsidence
(> 0.25 mm) between the 2- and 5-year follow-up. 1 porous-coated stem
was revised after the P-year follow-up, because of pain and implant fa
ilure (previously reported) and 1 cemented stem was revised after 5 ye
ars because of pain and osteolysis. In a subset of patients, all with
a femoral head made of aluminum oxide, the levels of metal were determ
ined using atomic adsorption spectrometry, Subsidence of the stem betw
een the 2- and 5-year follow-up was associated with increased levels o
f aluminum in the blood at 2 years. Generation of metallic particles f
rom abrasive wear of the stem followed by third body abrasion of the c
eramic femoral head could be one explanation of this finding. 5 hips w
hich had shown high levels of titanium and aluminum in joint fluid at
the 2-year follow-up displayed increased subsidence and developed prox
imal radiolucencies or osteolysis at the 5-year follow up. One of thes
e was the cemented hip which was subsequently revised.