A STOCHASTIC-MODEL OF POLYMER TRANSLOCATION DYNAMICS THROUGH BIOMEMBRANES

Authors
Citation
Pj. Park et W. Sung, A STOCHASTIC-MODEL OF POLYMER TRANSLOCATION DYNAMICS THROUGH BIOMEMBRANES, International journal of bifurcation and chaos in applied sciences and engineering, 8(5), 1998, pp. 927-931
Citations number
13
Categorie Soggetti
Mathematics,Mathematics,"Multidisciplinary Sciences
ISSN journal
02181274
Volume
8
Issue
5
Year of publication
1998
Pages
927 - 931
Database
ISI
SICI code
0218-1274(1998)8:5<927:ASOPTD>2.0.ZU;2-I
Abstract
The polymer translocation across membranes is studied as a stochastic process over a free energy barrier, where the mean first passage time is examined analytically as a measure of translocation rate. The noneq uilibrium fluctuations of chemical potential difference enhance direct ed transport of polymers, giving rise to a resonant activation. The tr anslocation time of a long-chain polymer is found to be very sensitive not only to the average value of chemical potential difference but al so to its fluctuation.