Severe cerebrovascular complications following cardiac surgical proced
ures remain a major concern, particularly in patients with significant
carotid atherosclerotic involvement (14% of perioperative stroke). Op
erative mortality for carotid operations in patients with documented C
oronary Artery Disease (CAD) may be as high as 20%. Seventy patients u
nderwent combined operations (unilateral carotid stenosis > 70%, unila
teral stenosis > 50% with ulcerated plaque or bilateral stenoses > 50%
; and this also included patients with unilateral occlusion). Cardiac
procedures were 69 coronary artery bypass grafts, four left ventricula
r aneurysmectomies, three aortic valve replacements and surgery on two
mitral valves. Seven perioperative deaths occurred, which were all ca
used by cardiac events. There were no perioperative strokes. Carotid e
ndarterectomy immediately before cardiopulmonary bypass is a safe and
expeditious approach to coexisting significant cardiac and carotid dis
ease. In our experience. technical details in monitoring and minimizin
g cerebral ischemia are possibly more crucial in these severe vasculop
athic patients. Moreover. it is probably advantageous from an economic
standpoint compared with other therapeutic treatments. (C) 1998 The I
nternational Society for Cardiovascular Surgery. Published by Elsevier
Science Ltd. All rights reserved.