D. Kopelman et al., PREVENTION OF LIMB LOSS IN CRITICAL ISCHEMIA BY ARTERIALIZATION OF THE SUPERFICIAL VENOUS SYSTEM - AN EXPERIMENTAL-STUDY IN DOGS, Cardiovascular surgery, 6(4), 1998, pp. 384-388
The possibility of ischaemic limb salvage by arterializing the superfi
cial venous system was examined in a canine study. The experiment was
carried out on lour healthy dogs in three stages. In the first stage,
collateral circulation to the hind limb was abolished. In the second s
tage, all branches of the common femoral artery were ligated, which cr
eated a model of ischaemia incompatible with limb survival. Revascular
ization was achieved by anastomosing the valvulotomized long saphenous
vein to the common femoral artery, proximal to its ligation. The dogs
were monitored for 2 weeks. All limbs maintained tissue oxygenation s
imilar to that of the control contralateral limb. in the third stage,
the artery was ligated proximal to the femoro-saphenous anastomosis an
d the limb monitored for 7 hours. Acute lass of motor function of the
limb resulted. In the present study, arterialization of the valvulotom
ized long saphenous vein prevented limb loss in critical ischaemia. (C
) 1998 The International Society for Cardiovascular Surgery. Published
by Elsevier Science Ltd. All rights reserved.