Objective. The aim of this study was to evaluate previous teacher repo
rts that children exposed to cocaine prenatally have more problem beha
viors. Methods. A historical, prospective design was used. Maternal su
bjects (n = 116) of 6-year-old singleton, term (greater than or equal
to 36 weeks) children, and the children's first-grade teachers (n = 10
2) agreed to participate. The child's first-grade teacher, blinded to
study design and exposure status, rated the child's behavior with the
Conners' Teacher Rating Scales (CTRS) and an investigator-developed sc
ale, the Problem Behavior Scale (PROBS 14), measuring behaviors report
ed by educators to be specific to cocaine exposure. Mothers were inter
viewed by telephone regarding demographic and socioeconomic factors. R
esults. Although the cocaine-exposed group had higher (more problem be
haviors) for each of the CTRS subscales, the overall multivariate anal
ysis of variance for the CTRS was not significant. Children exposed to
cocaine prenatally had higher scores (more problem behaviors) for 11
of the 14 PROBS items and the overall multivariate analysis of varianc
e relating prenatal cocaine exposure to the PROBS was significant (Wil
kes' lambda = .775), even after controlling for gender and prenatal ex
posure to alcohol and cigarettes. Conclusions. This pilot study suppor
ts that teachers blinded to exposure status of early elementary studen
ts did rate the cocaine-exposed group as demonstrating significantly m
ore problem behaviors than control children. Although an important fir
st step, postnatal factors that also may influence behavior were not e
valuated; hence, causation is not addressed.