IN-VITRO ACTIVITIES OF 15 ANTIMICROBIAL AGENTS AGAINST CLINICAL ISOLATES OF SOUTH-AFRICAN ENTEROCOCCI

Authors
STRUWIG MC BOTHA PL CHALKLEY LJ
Citation
Mc. Struwig et al., IN-VITRO ACTIVITIES OF 15 ANTIMICROBIAL AGENTS AGAINST CLINICAL ISOLATES OF SOUTH-AFRICAN ENTEROCOCCI, Antimicrobial agents and chemotherapy, 42(10), 1998, pp. 2752-2755
Citations number
24
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
42
Issue
10
Year of publication
1998
Pages
2752 - 2755
Database
ISI
SICI code
0066-4804(1998)42:10<2752:IAO1AA>2.0.ZU;2-G
Abstract
The activities of a panel of currently available antibiotics and the i nvestigational agents LY 333328, linezolid, CL 331,002, CL 329,998, mo xifloxacin (BAY 12-8039, trovafloxacin, and quinupristin-dalfopristin against 274 clinical isolates of enterococci were determined. No vanco mycin resistance or beta-lactamase production was observed. Except for 12 isolates tall non-Enterococcus faecalis) showing reduced susceptib ility to quinupristin-dalfopristin (MIC, greater than or equal to mu g /ml), the new agents exhibited promising in vitro antienterococcal act ivity.