Va. Mclaughlin et al., PENICILLIN RESISTANCE IN LABORATORY ISOLATES OF STREPTOCOCCUS-PNEUMONIAE, IN WESTERN-AUSTRALIA, 1990-1994, European journal of epidemiology, 14(6), 1998, pp. 611-615
Increasing frequency of penicillin resistance in Streptococcus pneumon
iae has been reported worldwide. We report on clinical isolates of pen
icillin-resistant pneumococci (PRP) in Western Australia (WA) from 199
0-1994. A retrospective survey of laboratories performing susceptibili
ty testing, or receiving isolates referred from rural areas found resi
stant on oxacillin disc screening, was undertaken. Four of 11 laborato
ries could provide data for the five year time period inclusive. Infor
mation was provided on susceptibility to penicillin, type of specimen,
date of isolation and; age, sex and race of individuals with PRP Peni
cillin resistance increased from 1.3 % to 9.0 % over the five year per
iod. PRP were rarely invasive. Highest age specific rates per 100,000
were found in children < 5 years (19.4) and adults greater than or equ
al to 60 years (5.1). Aboriginal ethnicity was associated with resista
nce. The increasing frequency of PRP in WA indicates the need for surv
eillance systems for their detection.