ANTIBODIES AGAINST HELICOBACTER-PYLORI WERE DETECTED IN THE CEREBROSPINAL-FLUID OBTAINED FROM PATIENTS WITH GUILLAIN-BARRE-SYNDROME

We examined the antibodies against Helicobacter pylori proteins in the cerebrospinal fluid (CSF) of 7 patients with Guillain-Barre syndrome (GBS). Crude H. pylori antigens, fractionated heat shock. protein (HSP ), and urease B (UB) from H. pylori antigens were separated by SDS-PAG E. With Western blot analysis, four of seven CSF samples bad several I gG antibodies against H. pylori proteins, including HSP and UB. No cro ss reactivity against Campylobacter jejuni was observed. These antibod ies may be involved in the immune responses of patients with GBS.