ECG CONDUCTION DELAYS ASSOCIATED WITH MASSIVE BUPROPION OVERDOSE

Background: Bupropion, a relatively new antidepressant, is highly rega rded for its safety profile in therapeutic doses and in the overdose. Seizure is the primary adverse reaction associated with bupropion over doses. Clinically significant cardiovascular complications are rare. C ase Report: We report the case of an adult male who ingested 9 g bupro pion and developed neurologic toxicity as well as intraventricular con duction disturbances on electrocardiogram. Cardiac monitoring of these patients should be considered.