CHIRAL MESOPOROUS TEMPLATED SILICAS AS HETEROGENEOUS INORGANIC-ORGANIC CATALYSTS IN THE ENANTIOSELECTIVE ALKYLATION OF BENZALDEHYDE

Authors
LASPERAS M BELLOCQ N BRUNEL D MOREAU P
Citation
M. Lasperas et al., CHIRAL MESOPOROUS TEMPLATED SILICAS AS HETEROGENEOUS INORGANIC-ORGANIC CATALYSTS IN THE ENANTIOSELECTIVE ALKYLATION OF BENZALDEHYDE, Tetrahedron : asymmetry, 9(17), 1998, pp. 3053-3064
Citations number
26
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
17
Year of publication
1998
Pages
3053 - 3064
Database
ISI
SICI code
0957-4166(1998)9:17<3053:CMTSAH>2.0.ZU;2-G
Abstract
New mesoporous templated silicas of the MCM-41 family covalently linke d to chiral ephedrine are used as heterogeneous chiral auxiliaries in the enantioselective alkylation of benzaldehyde by diethylzinc. Promis ing results are obtained with these inorganic-organic catalysts. Vario us factors which may affect the activity, selectivity and enantioselec tivity are studied. Comparison with homogeneous catalysis is carried o ut. (C) 1998 Elsevier Science Ltd. All rights reserved.