INTERACTION OF NEOGLYCOLIPIDS WITH ARTIFICIAL MEMBRANES AND ERYTHROCYTES - INFLUENCE OF THE LENGTH OF THE NEOGLYCOLIPID ETHOXY MOIETY

Authors
GELHAUSEN M BESSON F BONNIN S LAFONT D ROUX B
Citation
M. Gelhausen et al., INTERACTION OF NEOGLYCOLIPIDS WITH ARTIFICIAL MEMBRANES AND ERYTHROCYTES - INFLUENCE OF THE LENGTH OF THE NEOGLYCOLIPID ETHOXY MOIETY, Biotechnology letters, 20(8), 1998, pp. 713-716
Citations number
10
Categorie Soggetti
Biothechnology & Applied Migrobiology
Journal title
Biotechnology letters → ACNP
ISSN journal
01415492
Volume
20
Issue
8
Year of publication
1998
Pages
713 - 716
Database
ISI
SICI code
0141-5492(1998)20:8<713:IONWAM>2.0.ZU;2-4
Abstract
Lengthening the spacer of N-acetyl glucosaminyl oligoethoxy cholestero l neoglycolipids from one to seven ethoxy units modified neither the n eoglycolipid incorporation into liposomes nor the liposome sizes. More over, lengthening the spacer from three to seven units increased the 5 (6)-carboxyfluorescein leakage from mixed liposomes. These neoglycolip id-induced disturbances in membrane permeability were corroborated by determining their haemolytic activities.