DISSEMINATED INTRAVASCULAR COAGULATION (DIC) AND RHABDOMYOLYSIS IN FULMINANT VARICELLA INFECTION - CASE-REPORT AND REVIEW OF THE LITERATURE

Primary infection,vith varicella-zoster virus usually is a mild, self- limiting childhood illness. However, certain rare but potentially life -threatening complications can be associated with the disease. Adults and immunosuppressed patients are at increased risk for these events. We report a case of a patient on chronic immunosuppressants with fulmi nant varicella infection complicated by rhabdomyolysis and disseminate d intravascular coagulation, Mechanisms of muscle damage in viral dise ases might be direct invasion of skeletal muscle and/or induction of h armful cytokines, Aggressive fluid therapy alkalinization of urine and supportive measures correcting electrolyte imbalances, hypothermia an d hypoxemia should result in preservation or complete restoration of r enal function. Disseminated intravascular coagulation occurs in conjun ction with various diseases and may range from mild laboratory abnorma lities to fulminant lethal thrombosis and bleeding. Apart from elimina tion of the causative process therapeutic strategies are still highly disputed.