ISOMERIZATION-REACTIONS OF 7-SUBSTITUTED 6,14-BRIDGED THEBAINE DERIVATIVES (BENTLEY COMPOUNDS)

Authors
MARTON J GARADNAY S SZABO Z HOSZTAFI S MAKLEIT S
Citation
J. Marton et al., ISOMERIZATION-REACTIONS OF 7-SUBSTITUTED 6,14-BRIDGED THEBAINE DERIVATIVES (BENTLEY COMPOUNDS), Acta chemica Scandinavica, 52(10), 1998, pp. 1234-1238
Citations number
16
Categorie Soggetti
Chemistry,Biology
Journal title
Acta chemica Scandinavica → ACNP
ISSN journal
0904213X
Volume
52
Issue
10
Year of publication
1998
Pages
1234 - 1238
Database
ISI
SICI code
0904-213X(1998)52:10<1234:IO76TD>2.0.ZU;2-S
Abstract
Equilibration of the 7 alpha-->7 beta isomers of 7-substituted 6,14-et henomorphinanes has been accomplished, for the first time, in dipolar aprotic solvents by the application of bases with weak nucleophilic ch aracter. Transformation of the 7 beta-nitrile with phenylmagnesium bro mide led to a new type of 6,6 '-dimeric compound.