METHOD VALIDATION IN PHARMACEUTICAL ANALYSIS - FROM A GENERAL-APPROACH TO CAPILLARY-ELECTROPHORESIS

This paper gives a rapid review on analytical method validation with s pecial emphasis on capillary electrophoresis. The primary validation p arameters such, as accuracy, precision, specificity, linearity, and se nsitivity are defined; the evaluation procedures are outlined. The rec ent reports covering the applications on the subject are summarized an d discussed.