A PRACTICAL SYNTHESIS OF -BUTYL-4(5)-CHLORO-5(4)-HYDROXYMETHYL-1H-IMIDAZOLE

Authors
SHI YJ FREY LF TSCHAEN DM VERHOEVEN TR
Citation
Yj. Shi et al., A PRACTICAL SYNTHESIS OF -BUTYL-4(5)-CHLORO-5(4)-HYDROXYMETHYL-1H-IMIDAZOLE, Synthetic communications, 23(18), 1993, pp. 2623-2630
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthetic communications → ACNP
ISSN journal
00397911
Volume
23
Issue
18
Year of publication
1993
Pages
2623 - 2630
Database
ISI
SICI code
0039-7911(1993)23:18<2623:APSO->2.0.ZU;2-B
Abstract
A practical process for the synthesis of 2-butyl-4-hydroxymethyl imida zole (4) followed by chlorination to provide chloroimidazole 1 in an o verall 71% yield has been developed.