APPLICATION OF PHENYL SALICYLATE-SEPIOLITE SYSTEMS AS ULTRAVIOLET-RADIATION FILTERS

The interaction between phenyl salicylate and sepiolite has been studi ed using drug-clay systems obtained by melting and grinding. The sampl es have been characterized by powder Xray diffraction, differential th ermal and thermogravimetric analyses, and Vis-UV and FT-IR spectroscop ies. 'Free' water molecules are steadily substituted by the drug molec ules, without any chemical change as shown by FT-TR. The systems prepa red improved the protecting ability of the pure sepiolite or the pure drug against ultraviolet radiation, especially in the so-called 'C' ra nge (290-190 nm).